Tissue-specific transcript profiling for ABC transporters in the sequestering larvae of the phytophagous leaf beetle Chrysomela populi.
Identifieur interne : 001F96 ( Main/Exploration ); précédent : 001F95; suivant : 001F97Tissue-specific transcript profiling for ABC transporters in the sequestering larvae of the phytophagous leaf beetle Chrysomela populi.
Auteurs : Anja S. Strauss [Allemagne] ; Ding Wang [Allemagne] ; Magdalena Stock [Allemagne] ; René R. Gretscher [Allemagne] ; Marco Groth [Allemagne] ; Wilhelm Boland [Allemagne] ; Antje Burse [Allemagne]Source :
- PloS one [ 1932-6203 ] ; 2014.
Descripteurs français
- KwdFr :
- ARN messager (génétique), Analyse de profil d'expression de gènes (MeSH), Animaux (MeSH), Coléoptères (croissance et développement), Coléoptères (génétique), Interférence par ARN (MeSH), Larve (génétique), Phylogenèse (MeSH), Réaction de polymérisation en chaine en temps réel (MeSH), Transporteurs ABC (génétique).
- MESH :
- croissance et développement : Coléoptères.
- génétique : ARN messager, Coléoptères, Larve, Transporteurs ABC.
- Analyse de profil d'expression de gènes, Animaux, Interférence par ARN, Phylogenèse, Réaction de polymérisation en chaine en temps réel.
English descriptors
- KwdEn :
- MESH :
- chemical , genetics : ATP-Binding Cassette Transporters, RNA, Messenger.
- genetics : Coleoptera, Larva.
- growth & development : Coleoptera.
- Animals, Gene Expression Profiling, Phylogeny, RNA Interference, Real-Time Polymerase Chain Reaction.
Abstract
BACKGROUND
Insects evolved ingenious adaptations to use extraordinary food sources. Particularly, the diet of herbivores enriched with noxious plant secondary metabolites requires detoxification mechanisms. Sequestration, which involves the uptake, transfer, and concentration of occasionally modified phytochemicals into specialized tissues or hemolymph, is one of the most successful detoxification strategies found in most insect orders. Due to the ability of ATP-binding cassette (ABC) carriers to transport a wide range of molecules including phytochemicals and xenobiotics, it is highly likely that they play a role in this sequestration process. To shed light on the role of ABC proteins in sequestration, we describe an inventory of putative ABC transporters in various tissues in the sequestering juvenile poplar leaf beetle, Chrysomela populi.
RESULTS
In the transcriptome of C. populi, we predicted 65 ABC transporters. To link the proteins with a possible function, we performed comparative phylogenetic analyses with ABC transporters of other insects and of humans. While tissue-specific profiling of each ABC transporter subfamily suggests that ABCB, C and G influence the plant metabolite absorption in the gut, ABCC with 14 members is the preferred subfamily responsible for the excretion of these metabolites via Malpighian tubules. Moreover, salicin, which is sequestered from poplar plants, is translocated into the defensive glands for further deterrent production. In these glands and among all identified ABC transporters, an exceptionally high transcript level was observed only for Cpabc35 (Cpmrp). RNAi revealed the deficiency of other ABC pumps to compensate the function of CpABC35, demonstrating its key role during sequestration.
CONCLUSION
We provide the first comprehensive phylogenetic study of the ABC family in a phytophagous beetle species. RNA-seq data from different larval tissues propose the importance of ABC pumps to achieve a homeostasis of plant-derived compounds and offer a basis for future analyses of their physiological function in sequestration processes.
DOI: 10.1371/journal.pone.0098637
PubMed: 24887102
PubMed Central: PMC4041752
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Tissue-specific transcript profiling for ABC transporters in the sequestering larvae of the phytophagous leaf beetle Chrysomela populi.</title><author><name sortKey="Strauss, Anja S" sort="Strauss, Anja S" uniqKey="Strauss A" first="Anja S" last="Strauss">Anja S. Strauss</name><affiliation wicri:level="1"><nlm:affiliation>Max Planck Institute for Chemical Ecology, Beutenberg Campus, Hans-Knoell-Str. 8, D-07745 Jena, Thuringia, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Max Planck Institute for Chemical Ecology, Beutenberg Campus, Hans-Knoell-Str. 8, D-07745 Jena, Thuringia</wicri:regionArea><wicri:noRegion>Thuringia</wicri:noRegion><wicri:noRegion>Thuringia</wicri:noRegion><wicri:noRegion>Thuringia</wicri:noRegion></affiliation></author><author><name sortKey="Wang, Ding" sort="Wang, Ding" uniqKey="Wang D" first="Ding" last="Wang">Ding Wang</name><affiliation wicri:level="1"><nlm:affiliation>Max Planck Institute for Chemical Ecology, Beutenberg Campus, Hans-Knoell-Str. 8, D-07745 Jena, Thuringia, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Max Planck Institute for Chemical Ecology, Beutenberg Campus, Hans-Knoell-Str. 8, D-07745 Jena, Thuringia</wicri:regionArea><wicri:noRegion>Thuringia</wicri:noRegion><wicri:noRegion>Thuringia</wicri:noRegion><wicri:noRegion>Thuringia</wicri:noRegion></affiliation></author><author><name sortKey="Stock, Magdalena" sort="Stock, Magdalena" uniqKey="Stock M" first="Magdalena" last="Stock">Magdalena Stock</name><affiliation wicri:level="1"><nlm:affiliation>Max Planck Institute for Chemical Ecology, Beutenberg Campus, Hans-Knoell-Str. 8, D-07745 Jena, Thuringia, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Max Planck Institute for Chemical Ecology, Beutenberg Campus, Hans-Knoell-Str. 8, D-07745 Jena, Thuringia</wicri:regionArea><wicri:noRegion>Thuringia</wicri:noRegion><wicri:noRegion>Thuringia</wicri:noRegion><wicri:noRegion>Thuringia</wicri:noRegion></affiliation></author><author><name sortKey="Gretscher, Rene R" sort="Gretscher, Rene R" uniqKey="Gretscher R" first="René R" last="Gretscher">René R. Gretscher</name><affiliation wicri:level="1"><nlm:affiliation>Max Planck Institute for Chemical Ecology, Beutenberg Campus, Hans-Knoell-Str. 8, D-07745 Jena, Thuringia, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Max Planck Institute for Chemical Ecology, Beutenberg Campus, Hans-Knoell-Str. 8, D-07745 Jena, Thuringia</wicri:regionArea><wicri:noRegion>Thuringia</wicri:noRegion><wicri:noRegion>Thuringia</wicri:noRegion><wicri:noRegion>Thuringia</wicri:noRegion></affiliation></author><author><name sortKey="Groth, Marco" sort="Groth, Marco" uniqKey="Groth M" first="Marco" last="Groth">Marco Groth</name><affiliation wicri:level="1"><nlm:affiliation>Leibniz Institute for Age Research - Fritz Lipmann Institute, Beutenbergstr. 11, D-07745 Jena, Thuringia, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Leibniz Institute for Age Research - Fritz Lipmann Institute, Beutenbergstr. 11, D-07745 Jena, Thuringia</wicri:regionArea><wicri:noRegion>Thuringia</wicri:noRegion><wicri:noRegion>Thuringia</wicri:noRegion><wicri:noRegion>Thuringia</wicri:noRegion></affiliation></author><author><name sortKey="Boland, Wilhelm" sort="Boland, Wilhelm" uniqKey="Boland W" first="Wilhelm" last="Boland">Wilhelm Boland</name><affiliation wicri:level="1"><nlm:affiliation>Max Planck Institute for Chemical Ecology, Beutenberg Campus, Hans-Knoell-Str. 8, D-07745 Jena, Thuringia, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Max Planck Institute for Chemical Ecology, Beutenberg Campus, Hans-Knoell-Str. 8, D-07745 Jena, Thuringia</wicri:regionArea><wicri:noRegion>Thuringia</wicri:noRegion><wicri:noRegion>Thuringia</wicri:noRegion><wicri:noRegion>Thuringia</wicri:noRegion></affiliation></author><author><name sortKey="Burse, Antje" sort="Burse, Antje" uniqKey="Burse A" first="Antje" last="Burse">Antje Burse</name><affiliation wicri:level="1"><nlm:affiliation>Max Planck Institute for Chemical Ecology, Beutenberg Campus, Hans-Knoell-Str. 8, D-07745 Jena, Thuringia, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Max Planck Institute for Chemical Ecology, Beutenberg Campus, Hans-Knoell-Str. 8, D-07745 Jena, Thuringia</wicri:regionArea><wicri:noRegion>Thuringia</wicri:noRegion><wicri:noRegion>Thuringia</wicri:noRegion><wicri:noRegion>Thuringia</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2014">2014</date><idno type="RBID">pubmed:24887102</idno><idno type="pmid">24887102</idno><idno type="doi">10.1371/journal.pone.0098637</idno><idno type="pmc">PMC4041752</idno><idno type="wicri:Area/Main/Corpus">002160</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">002160</idno><idno type="wicri:Area/Main/Curation">002160</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">002160</idno><idno type="wicri:Area/Main/Exploration">002160</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Tissue-specific transcript profiling for ABC transporters in the sequestering larvae of the phytophagous leaf beetle Chrysomela populi.</title><author><name sortKey="Strauss, Anja S" sort="Strauss, Anja S" uniqKey="Strauss A" first="Anja S" last="Strauss">Anja S. Strauss</name><affiliation wicri:level="1"><nlm:affiliation>Max Planck Institute for Chemical Ecology, Beutenberg Campus, Hans-Knoell-Str. 8, D-07745 Jena, Thuringia, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Max Planck Institute for Chemical Ecology, Beutenberg Campus, Hans-Knoell-Str. 8, D-07745 Jena, Thuringia</wicri:regionArea><wicri:noRegion>Thuringia</wicri:noRegion><wicri:noRegion>Thuringia</wicri:noRegion><wicri:noRegion>Thuringia</wicri:noRegion></affiliation></author><author><name sortKey="Wang, Ding" sort="Wang, Ding" uniqKey="Wang D" first="Ding" last="Wang">Ding Wang</name><affiliation wicri:level="1"><nlm:affiliation>Max Planck Institute for Chemical Ecology, Beutenberg Campus, Hans-Knoell-Str. 8, D-07745 Jena, Thuringia, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Max Planck Institute for Chemical Ecology, Beutenberg Campus, Hans-Knoell-Str. 8, D-07745 Jena, Thuringia</wicri:regionArea><wicri:noRegion>Thuringia</wicri:noRegion><wicri:noRegion>Thuringia</wicri:noRegion><wicri:noRegion>Thuringia</wicri:noRegion></affiliation></author><author><name sortKey="Stock, Magdalena" sort="Stock, Magdalena" uniqKey="Stock M" first="Magdalena" last="Stock">Magdalena Stock</name><affiliation wicri:level="1"><nlm:affiliation>Max Planck Institute for Chemical Ecology, Beutenberg Campus, Hans-Knoell-Str. 8, D-07745 Jena, Thuringia, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Max Planck Institute for Chemical Ecology, Beutenberg Campus, Hans-Knoell-Str. 8, D-07745 Jena, Thuringia</wicri:regionArea><wicri:noRegion>Thuringia</wicri:noRegion><wicri:noRegion>Thuringia</wicri:noRegion><wicri:noRegion>Thuringia</wicri:noRegion></affiliation></author><author><name sortKey="Gretscher, Rene R" sort="Gretscher, Rene R" uniqKey="Gretscher R" first="René R" last="Gretscher">René R. Gretscher</name><affiliation wicri:level="1"><nlm:affiliation>Max Planck Institute for Chemical Ecology, Beutenberg Campus, Hans-Knoell-Str. 8, D-07745 Jena, Thuringia, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Max Planck Institute for Chemical Ecology, Beutenberg Campus, Hans-Knoell-Str. 8, D-07745 Jena, Thuringia</wicri:regionArea><wicri:noRegion>Thuringia</wicri:noRegion><wicri:noRegion>Thuringia</wicri:noRegion><wicri:noRegion>Thuringia</wicri:noRegion></affiliation></author><author><name sortKey="Groth, Marco" sort="Groth, Marco" uniqKey="Groth M" first="Marco" last="Groth">Marco Groth</name><affiliation wicri:level="1"><nlm:affiliation>Leibniz Institute for Age Research - Fritz Lipmann Institute, Beutenbergstr. 11, D-07745 Jena, Thuringia, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Leibniz Institute for Age Research - Fritz Lipmann Institute, Beutenbergstr. 11, D-07745 Jena, Thuringia</wicri:regionArea><wicri:noRegion>Thuringia</wicri:noRegion><wicri:noRegion>Thuringia</wicri:noRegion><wicri:noRegion>Thuringia</wicri:noRegion></affiliation></author><author><name sortKey="Boland, Wilhelm" sort="Boland, Wilhelm" uniqKey="Boland W" first="Wilhelm" last="Boland">Wilhelm Boland</name><affiliation wicri:level="1"><nlm:affiliation>Max Planck Institute for Chemical Ecology, Beutenberg Campus, Hans-Knoell-Str. 8, D-07745 Jena, Thuringia, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Max Planck Institute for Chemical Ecology, Beutenberg Campus, Hans-Knoell-Str. 8, D-07745 Jena, Thuringia</wicri:regionArea><wicri:noRegion>Thuringia</wicri:noRegion><wicri:noRegion>Thuringia</wicri:noRegion><wicri:noRegion>Thuringia</wicri:noRegion></affiliation></author><author><name sortKey="Burse, Antje" sort="Burse, Antje" uniqKey="Burse A" first="Antje" last="Burse">Antje Burse</name><affiliation wicri:level="1"><nlm:affiliation>Max Planck Institute for Chemical Ecology, Beutenberg Campus, Hans-Knoell-Str. 8, D-07745 Jena, Thuringia, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Max Planck Institute for Chemical Ecology, Beutenberg Campus, Hans-Knoell-Str. 8, D-07745 Jena, Thuringia</wicri:regionArea><wicri:noRegion>Thuringia</wicri:noRegion><wicri:noRegion>Thuringia</wicri:noRegion><wicri:noRegion>Thuringia</wicri:noRegion></affiliation></author></analytic><series><title level="j">PloS one</title><idno type="eISSN">1932-6203</idno><imprint><date when="2014" type="published">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>ATP-Binding Cassette Transporters (genetics)</term><term>Animals (MeSH)</term><term>Coleoptera (genetics)</term><term>Coleoptera (growth & development)</term><term>Gene Expression Profiling (MeSH)</term><term>Larva (genetics)</term><term>Phylogeny (MeSH)</term><term>RNA Interference (MeSH)</term><term>RNA, Messenger (genetics)</term><term>Real-Time Polymerase Chain Reaction (MeSH)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>ARN messager (génétique)</term><term>Analyse de profil d'expression de gènes (MeSH)</term><term>Animaux (MeSH)</term><term>Coléoptères (croissance et développement)</term><term>Coléoptères (génétique)</term><term>Interférence par ARN (MeSH)</term><term>Larve (génétique)</term><term>Phylogenèse (MeSH)</term><term>Réaction de polymérisation en chaine en temps réel (MeSH)</term><term>Transporteurs ABC (génétique)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>ATP-Binding Cassette Transporters</term><term>RNA, Messenger</term></keywords><keywords scheme="MESH" qualifier="croissance et développement" xml:lang="fr"><term>Coléoptères</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Coleoptera</term><term>Larva</term></keywords><keywords scheme="MESH" qualifier="growth & development" xml:lang="en"><term>Coleoptera</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>ARN messager</term><term>Coléoptères</term><term>Larve</term><term>Transporteurs ABC</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Gene Expression Profiling</term><term>Phylogeny</term><term>RNA Interference</term><term>Real-Time Polymerase Chain Reaction</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Analyse de profil d'expression de gènes</term><term>Animaux</term><term>Interférence par ARN</term><term>Phylogenèse</term><term>Réaction de polymérisation en chaine en temps réel</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p><b>BACKGROUND</b></p><p>Insects evolved ingenious adaptations to use extraordinary food sources. Particularly, the diet of herbivores enriched with noxious plant secondary metabolites requires detoxification mechanisms. Sequestration, which involves the uptake, transfer, and concentration of occasionally modified phytochemicals into specialized tissues or hemolymph, is one of the most successful detoxification strategies found in most insect orders. Due to the ability of ATP-binding cassette (ABC) carriers to transport a wide range of molecules including phytochemicals and xenobiotics, it is highly likely that they play a role in this sequestration process. To shed light on the role of ABC proteins in sequestration, we describe an inventory of putative ABC transporters in various tissues in the sequestering juvenile poplar leaf beetle, Chrysomela populi.</p></div><div type="abstract" xml:lang="en"><p><b>RESULTS</b></p><p>In the transcriptome of C. populi, we predicted 65 ABC transporters. To link the proteins with a possible function, we performed comparative phylogenetic analyses with ABC transporters of other insects and of humans. While tissue-specific profiling of each ABC transporter subfamily suggests that ABCB, C and G influence the plant metabolite absorption in the gut, ABCC with 14 members is the preferred subfamily responsible for the excretion of these metabolites via Malpighian tubules. Moreover, salicin, which is sequestered from poplar plants, is translocated into the defensive glands for further deterrent production. In these glands and among all identified ABC transporters, an exceptionally high transcript level was observed only for Cpabc35 (Cpmrp). RNAi revealed the deficiency of other ABC pumps to compensate the function of CpABC35, demonstrating its key role during sequestration.</p></div><div type="abstract" xml:lang="en"><p><b>CONCLUSION</b></p><p>We provide the first comprehensive phylogenetic study of the ABC family in a phytophagous beetle species. RNA-seq data from different larval tissues propose the importance of ABC pumps to achieve a homeostasis of plant-derived compounds and offer a basis for future analyses of their physiological function in sequestration processes.</p></div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">24887102</PMID><DateCompleted><Year>2015</Year><Month>01</Month><Day>20</Day></DateCompleted><DateRevised><Year>2018</Year><Month>11</Month><Day>13</Day></DateRevised><Article PubModel="Electronic-eCollection"><Journal><ISSN IssnType="Electronic">1932-6203</ISSN><JournalIssue CitedMedium="Internet"><Volume>9</Volume><Issue>6</Issue><PubDate><Year>2014</Year></PubDate></JournalIssue><Title>PloS one</Title><ISOAbbreviation>PLoS One</ISOAbbreviation></Journal><ArticleTitle>Tissue-specific transcript profiling for ABC transporters in the sequestering larvae of the phytophagous leaf beetle Chrysomela populi.</ArticleTitle><Pagination><MedlinePgn>e98637</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1371/journal.pone.0098637</ELocationID><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Insects evolved ingenious adaptations to use extraordinary food sources. Particularly, the diet of herbivores enriched with noxious plant secondary metabolites requires detoxification mechanisms. Sequestration, which involves the uptake, transfer, and concentration of occasionally modified phytochemicals into specialized tissues or hemolymph, is one of the most successful detoxification strategies found in most insect orders. Due to the ability of ATP-binding cassette (ABC) carriers to transport a wide range of molecules including phytochemicals and xenobiotics, it is highly likely that they play a role in this sequestration process. To shed light on the role of ABC proteins in sequestration, we describe an inventory of putative ABC transporters in various tissues in the sequestering juvenile poplar leaf beetle, Chrysomela populi.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">In the transcriptome of C. populi, we predicted 65 ABC transporters. To link the proteins with a possible function, we performed comparative phylogenetic analyses with ABC transporters of other insects and of humans. While tissue-specific profiling of each ABC transporter subfamily suggests that ABCB, C and G influence the plant metabolite absorption in the gut, ABCC with 14 members is the preferred subfamily responsible for the excretion of these metabolites via Malpighian tubules. Moreover, salicin, which is sequestered from poplar plants, is translocated into the defensive glands for further deterrent production. In these glands and among all identified ABC transporters, an exceptionally high transcript level was observed only for Cpabc35 (Cpmrp). RNAi revealed the deficiency of other ABC pumps to compensate the function of CpABC35, demonstrating its key role during sequestration.</AbstractText><AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">We provide the first comprehensive phylogenetic study of the ABC family in a phytophagous beetle species. RNA-seq data from different larval tissues propose the importance of ABC pumps to achieve a homeostasis of plant-derived compounds and offer a basis for future analyses of their physiological function in sequestration processes.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Strauss</LastName><ForeName>Anja S</ForeName><Initials>AS</Initials><AffiliationInfo><Affiliation>Max Planck Institute for Chemical Ecology, Beutenberg Campus, Hans-Knoell-Str. 8, D-07745 Jena, Thuringia, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wang</LastName><ForeName>Ding</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Max Planck Institute for Chemical Ecology, Beutenberg Campus, Hans-Knoell-Str. 8, D-07745 Jena, Thuringia, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Stock</LastName><ForeName>Magdalena</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Max Planck Institute for Chemical Ecology, Beutenberg Campus, Hans-Knoell-Str. 8, D-07745 Jena, Thuringia, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gretscher</LastName><ForeName>René R</ForeName><Initials>RR</Initials><AffiliationInfo><Affiliation>Max Planck Institute for Chemical Ecology, Beutenberg Campus, Hans-Knoell-Str. 8, D-07745 Jena, Thuringia, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Groth</LastName><ForeName>Marco</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Leibniz Institute for Age Research - Fritz Lipmann Institute, Beutenbergstr. 11, D-07745 Jena, Thuringia, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Boland</LastName><ForeName>Wilhelm</ForeName><Initials>W</Initials><AffiliationInfo><Affiliation>Max Planck Institute for Chemical Ecology, Beutenberg Campus, Hans-Knoell-Str. 8, D-07745 Jena, Thuringia, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Burse</LastName><ForeName>Antje</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Max Planck Institute for Chemical Ecology, Beutenberg Campus, Hans-Knoell-Str. 8, D-07745 Jena, Thuringia, Germany.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2014</Year><Month>06</Month><Day>02</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>PLoS One</MedlineTA><NlmUniqueID>101285081</NlmUniqueID><ISSNLinking>1932-6203</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D018528">ATP-Binding Cassette Transporters</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D012333">RNA, Messenger</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D018528" MajorTopicYN="N">ATP-Binding Cassette Transporters</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D000818" MajorTopicYN="N">Animals</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D001517" MajorTopicYN="N">Coleoptera</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName><QualifierName UI="Q000254" MajorTopicYN="N">growth & development</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D020869" MajorTopicYN="Y">Gene Expression Profiling</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007814" MajorTopicYN="N">Larva</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D010802" MajorTopicYN="N">Phylogeny</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D034622" MajorTopicYN="N">RNA Interference</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012333" MajorTopicYN="N">RNA, Messenger</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D060888" MajorTopicYN="N">Real-Time Polymerase Chain Reaction</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2014</Year><Month>01</Month><Day>31</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2014</Year><Month>05</Month><Day>05</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2014</Year><Month>6</Month><Day>3</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2014</Year><Month>6</Month><Day>3</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2015</Year><Month>1</Month><Day>21</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>epublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">24887102</ArticleId><ArticleId IdType="doi">10.1371/journal.pone.0098637</ArticleId><ArticleId IdType="pii">PONE-D-14-04479</ArticleId><ArticleId IdType="pmc">PMC4041752</ArticleId></ArticleIdList><ReferenceList><Reference><Citation>Essays Biochem. 2011 Sep 7;50(1):179-207</Citation><ArticleIdList><ArticleId IdType="pubmed">21967058</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Cancer Res. 2009 Jan;7(1):79-87</Citation><ArticleIdList><ArticleId IdType="pubmed">19147539</ArticleId></ArticleIdList></Reference><Reference><Citation>Bioinformatics. 2006 Nov 1;22(21):2688-90</Citation><ArticleIdList><ArticleId IdType="pubmed">16928733</ArticleId></ArticleIdList></Reference><Reference><Citation>Biochem Genet. 1975 Oct;13(9-10):603-13</Citation><ArticleIdList><ArticleId IdType="pubmed">812484</ArticleId></ArticleIdList></Reference><Reference><Citation>J Biol Chem. 2008 Jul 11;283(28):19219-28</Citation><ArticleIdList><ArticleId IdType="pubmed">18482980</ArticleId></ArticleIdList></Reference><Reference><Citation>Biochemistry. 2010 Jun 22;49(24):4945-56</Citation><ArticleIdList><ArticleId IdType="pubmed">20481466</ArticleId></ArticleIdList></Reference><Reference><Citation>J Biol Chem. 2007 May 18;282(20):14752-60</Citation><ArticleIdList><ArticleId IdType="pubmed">17392269</ArticleId></ArticleIdList></Reference><Reference><Citation>BMC Genomics. 2013;14:317</Citation><ArticleIdList><ArticleId IdType="pubmed">23663308</ArticleId></ArticleIdList></Reference><Reference><Citation>Nucleic Acids Res. 2012 Jan;40(Database issue):D290-301</Citation><ArticleIdList><ArticleId IdType="pubmed">22127870</ArticleId></ArticleIdList></Reference><Reference><Citation>PLoS One. 2012;7(9):e45995</Citation><ArticleIdList><ArticleId IdType="pubmed">23049917</ArticleId></ArticleIdList></Reference><Reference><Citation>Essays Biochem. 2011 Sep 7;50(1):145-60</Citation><ArticleIdList><ArticleId IdType="pubmed">21967056</ArticleId></ArticleIdList></Reference><Reference><Citation>Biochem Biophys Res Commun. 2012 Feb 24;418(4):736-41</Citation><ArticleIdList><ArticleId IdType="pubmed">22306008</ArticleId></ArticleIdList></Reference><Reference><Citation>Cell Stress Chaperones. 2005 Spring;10(1):7-11</Citation><ArticleIdList><ArticleId IdType="pubmed">15832942</ArticleId></ArticleIdList></Reference><Reference><Citation>Biochem Biophys Res Commun. 2008 May 2;369(2):369-75</Citation><ArticleIdList><ArticleId IdType="pubmed">18279659</ArticleId></ArticleIdList></Reference><Reference><Citation>Insect Biochem Mol Biol. 2013 Aug;43(8):627-34</Citation><ArticleIdList><ArticleId IdType="pubmed">23648830</ArticleId></ArticleIdList></Reference><Reference><Citation>Proc Biol Sci. 2012 Oct 22;279(1745):4126-34</Citation><ArticleIdList><ArticleId IdType="pubmed">22874750</ArticleId></ArticleIdList></Reference><Reference><Citation>Biochim Biophys Acta. 1999 Jul 15;1419(2):173-85</Citation><ArticleIdList><ArticleId IdType="pubmed">10407069</ArticleId></ArticleIdList></Reference><Reference><Citation>BMC Genomics. 2013;14:185</Citation><ArticleIdList><ArticleId IdType="pubmed">23496936</ArticleId></ArticleIdList></Reference><Reference><Citation>Cancer Cell. 2004 Aug;6(2):129-37</Citation><ArticleIdList><ArticleId IdType="pubmed">15324696</ArticleId></ArticleIdList></Reference><Reference><Citation>Proc Biol Sci. 2013 May 22;280(1759):20123089</Citation><ArticleIdList><ArticleId IdType="pubmed">23516239</ArticleId></ArticleIdList></Reference><Reference><Citation>Heredity (Edinb). 2000 Aug;85 ( Pt 2):184-90</Citation><ArticleIdList><ArticleId IdType="pubmed">11012721</ArticleId></ArticleIdList></Reference><Reference><Citation>Proc Natl Acad Sci U S A. 2001 Mar 27;98(7):3909-14</Citation><ArticleIdList><ArticleId IdType="pubmed">11259651</ArticleId></ArticleIdList></Reference><Reference><Citation>Mar Environ Res. 2010;69 Suppl:S11-3</Citation><ArticleIdList><ArticleId IdType="pubmed">19926124</ArticleId></ArticleIdList></Reference><Reference><Citation>Cold Spring Harb Perspect Med. 2013 Feb;3(2):a009514</Citation><ArticleIdList><ArticleId IdType="pubmed">23378596</ArticleId></ArticleIdList></Reference><Reference><Citation>J Chem Ecol. 2002 Feb;28(2):317-31</Citation><ArticleIdList><ArticleId IdType="pubmed">11925070</ArticleId></ArticleIdList></Reference><Reference><Citation>Essays Biochem. 2011 Sep 7;50(1):1-17</Citation><ArticleIdList><ArticleId IdType="pubmed">21967049</ArticleId></ArticleIdList></Reference><Reference><Citation>Essays Biochem. 2011 Sep 7;50(1):209-32</Citation><ArticleIdList><ArticleId IdType="pubmed">21967059</ArticleId></ArticleIdList></Reference><Reference><Citation>Curr Med Chem. 2008;15(20):1981-2039</Citation><ArticleIdList><ArticleId IdType="pubmed">18691054</ArticleId></ArticleIdList></Reference><Reference><Citation>Methods. 2001 Dec;25(4):402-8</Citation><ArticleIdList><ArticleId IdType="pubmed">11846609</ArticleId></ArticleIdList></Reference><Reference><Citation>Insect Biochem Mol Biol. 2013 Jul;43(7):562-71</Citation><ArticleIdList><ArticleId IdType="pubmed">23567590</ArticleId></ArticleIdList></Reference><Reference><Citation>Genome Biol. 2010;11(10):R106</Citation><ArticleIdList><ArticleId IdType="pubmed">20979621</ArticleId></ArticleIdList></Reference><Reference><Citation>Biochim Biophys Acta. 2012 Sep;1822(9):1387-96</Citation><ArticleIdList><ArticleId IdType="pubmed">22366764</ArticleId></ArticleIdList></Reference><Reference><Citation>Proc Natl Acad Sci U S A. 2012 Mar 13;109(11):4152-7</Citation><ArticleIdList><ArticleId IdType="pubmed">22375032</ArticleId></ArticleIdList></Reference><Reference><Citation>PLoS One. 2007;2(4):e360</Citation><ArticleIdList><ArticleId IdType="pubmed">17426809</ArticleId></ArticleIdList></Reference><Reference><Citation>Insect Biochem Mol Biol. 2005 Mar;35(3):231-40</Citation><ArticleIdList><ArticleId IdType="pubmed">15705502</ArticleId></ArticleIdList></Reference><Reference><Citation>Comp Biochem Physiol C Toxicol Pharmacol. 2004 Mar;137(3):261-9</Citation><ArticleIdList><ArticleId IdType="pubmed">15171950</ArticleId></ArticleIdList></Reference><Reference><Citation>Genome Res. 2001 Jul;11(7):1156-66</Citation><ArticleIdList><ArticleId IdType="pubmed">11435397</ArticleId></ArticleIdList></Reference><Reference><Citation>Annu Rev Microbiol. 2002;56:93-116</Citation><ArticleIdList><ArticleId IdType="pubmed">12142484</ArticleId></ArticleIdList></Reference><Reference><Citation>Pflugers Arch. 2007 Feb;453(5):581-9</Citation><ArticleIdList><ArticleId IdType="pubmed">16586097</ArticleId></ArticleIdList></Reference><Reference><Citation>Biochim Biophys Acta. 1996 Oct 24;1291(2):155-62</Citation><ArticleIdList><ArticleId IdType="pubmed">8898877</ArticleId></ArticleIdList></Reference><Reference><Citation>Biochim Biophys Acta. 1999 Dec 6;1461(2):395-404</Citation><ArticleIdList><ArticleId IdType="pubmed">10581369</ArticleId></ArticleIdList></Reference><Reference><Citation>Insect Mol Biol. 2011 Apr;20(2):243-56</Citation><ArticleIdList><ArticleId IdType="pubmed">21199020</ArticleId></ArticleIdList></Reference><Reference><Citation>J Insect Physiol. 2006 Apr;52(4):365-78</Citation><ArticleIdList><ArticleId IdType="pubmed">16310213</ArticleId></ArticleIdList></Reference><Reference><Citation>J Biol Chem. 2012 Apr 13;287(16):12679-90</Citation><ArticleIdList><ArticleId IdType="pubmed">22294697</ArticleId></ArticleIdList></Reference><Reference><Citation>Genes Cells. 2011 Apr;16(4):331-42</Citation><ArticleIdList><ArticleId IdType="pubmed">21294818</ArticleId></ArticleIdList></Reference><Reference><Citation>PLoS Genet. 2010 Dec;6(12):e1001248</Citation><ArticleIdList><ArticleId IdType="pubmed">21187898</ArticleId></ArticleIdList></Reference><Reference><Citation>Essays Biochem. 2011 Sep 7;50(1):19-42</Citation><ArticleIdList><ArticleId IdType="pubmed">21967050</ArticleId></ArticleIdList></Reference><Reference><Citation>Nucleic Acids Res. 2008 Jan;36(Database issue):D281-8</Citation><ArticleIdList><ArticleId IdType="pubmed">18039703</ArticleId></ArticleIdList></Reference><Reference><Citation>Nat Protoc. 2013 Sep;8(9):1765-86</Citation><ArticleIdList><ArticleId IdType="pubmed">23975260</ArticleId></ArticleIdList></Reference><Reference><Citation>PLoS Genet. 2013;9(7):e1003596</Citation><ArticleIdList><ArticleId IdType="pubmed">23874211</ArticleId></ArticleIdList></Reference><Reference><Citation>Pflugers Arch. 2007 Feb;453(5):569-79</Citation><ArticleIdList><ArticleId IdType="pubmed">16858612</ArticleId></ArticleIdList></Reference><Reference><Citation>Essays Biochem. 2011 Sep 7;50(1):265-90</Citation><ArticleIdList><ArticleId IdType="pubmed">21967062</ArticleId></ArticleIdList></Reference><Reference><Citation>J Exp Biol. 2008 Mar;211(Pt 6):890-9</Citation><ArticleIdList><ArticleId IdType="pubmed">18310115</ArticleId></ArticleIdList></Reference><Reference><Citation>Biochim Biophys Acta. 2010 Jun;1798(6):1135-43</Citation><ArticleIdList><ArticleId IdType="pubmed">20188065</ArticleId></ArticleIdList></Reference><Reference><Citation>Toxicol Sci. 2011 Apr;120(2):519-28</Citation><ArticleIdList><ArticleId IdType="pubmed">21266531</ArticleId></ArticleIdList></Reference><Reference><Citation>Nat Biotechnol. 2011 Jul;29(7):644-52</Citation><ArticleIdList><ArticleId IdType="pubmed">21572440</ArticleId></ArticleIdList></Reference><Reference><Citation>J Mol Biol. 1984 Dec 15;180(3):437-55</Citation><ArticleIdList><ArticleId IdType="pubmed">6084717</ArticleId></ArticleIdList></Reference><Reference><Citation>Nucleic Acids Res. 2002 Jul 15;30(14):3059-66</Citation><ArticleIdList><ArticleId IdType="pubmed">12136088</ArticleId></ArticleIdList></Reference><Reference><Citation>Genome Biol. 2004;5(10):R80</Citation><ArticleIdList><ArticleId IdType="pubmed">15461798</ArticleId></ArticleIdList></Reference><Reference><Citation>J Chem Ecol. 1990 Jan;16(1):211-22</Citation><ArticleIdList><ArticleId IdType="pubmed">24264908</ArticleId></ArticleIdList></Reference><Reference><Citation>Xenobiotica. 2008 Jul;38(7-8):802-32</Citation><ArticleIdList><ArticleId IdType="pubmed">18668431</ArticleId></ArticleIdList></Reference><Reference><Citation>Comp Biochem Physiol B Biochem Mol Biol. 1998 Dec;121(4):443-50</Citation><ArticleIdList><ArticleId IdType="pubmed">9972316</ArticleId></ArticleIdList></Reference><Reference><Citation>Insect Mol Biol. 2002 Jun;11(3):217-22</Citation><ArticleIdList><ArticleId IdType="pubmed">12000640</ArticleId></ArticleIdList></Reference><Reference><Citation>PLoS One. 2012;7(5):e37378</Citation><ArticleIdList><ArticleId IdType="pubmed">22655043</ArticleId></ArticleIdList></Reference><Reference><Citation>Proc Natl Acad Sci U S A. 2011 Sep 13;108(37):15336-41</Citation><ArticleIdList><ArticleId IdType="pubmed">21873242</ArticleId></ArticleIdList></Reference><Reference><Citation>Pflugers Arch. 2007 Feb;453(5):591-600</Citation><ArticleIdList><ArticleId IdType="pubmed">16710701</ArticleId></ArticleIdList></Reference><Reference><Citation>Pflugers Arch. 2007 Feb;453(5):703-18</Citation><ArticleIdList><ArticleId IdType="pubmed">16897043</ArticleId></ArticleIdList></Reference><Reference><Citation>Biol Chem. 2011 Jan;392(1-2):61-6</Citation><ArticleIdList><ArticleId IdType="pubmed">21194361</ArticleId></ArticleIdList></Reference><Reference><Citation>BMC Genomics. 2011;12:491</Citation><ArticleIdList><ArticleId IdType="pubmed">21981826</ArticleId></ArticleIdList></Reference><Reference><Citation>FEBS J. 2011 Sep;278(18):3215-25</Citation><ArticleIdList><ArticleId IdType="pubmed">21554546</ArticleId></ArticleIdList></Reference><Reference><Citation>Pharmacol Ther. 2007 Jun;114(3):345-58</Citation><ArticleIdList><ArticleId IdType="pubmed">17368550</ArticleId></ArticleIdList></Reference><Reference><Citation>Curr Protoc Bioinformatics. 2010 Dec;Chapter 11:Unit 11.7</Citation><ArticleIdList><ArticleId IdType="pubmed">21154709</ArticleId></ArticleIdList></Reference><Reference><Citation>Clin Chem. 2009 Apr;55(4):611-22</Citation><ArticleIdList><ArticleId IdType="pubmed">19246619</ArticleId></ArticleIdList></Reference><Reference><Citation>Proc Natl Acad Sci U S A. 2004 Sep 21;101(38):13808-13</Citation><ArticleIdList><ArticleId IdType="pubmed">15365181</ArticleId></ArticleIdList></Reference><Reference><Citation>BMC Biol. 2013;11:69</Citation><ArticleIdList><ArticleId IdType="pubmed">23773777</ArticleId></ArticleIdList></Reference><Reference><Citation>Biochem Biophys Res Commun. 2004 Feb 27;315(1):166-73</Citation><ArticleIdList><ArticleId IdType="pubmed">15013441</ArticleId></ArticleIdList></Reference><Reference><Citation>Biochim Biophys Acta. 2009 Jul;1791(7):584-93</Citation><ArticleIdList><ArticleId IdType="pubmed">19416657</ArticleId></ArticleIdList></Reference><Reference><Citation>Pflugers Arch. 2007 Feb;453(5):611-20</Citation><ArticleIdList><ArticleId IdType="pubmed">17051391</ArticleId></ArticleIdList></Reference><Reference><Citation>Elife. 2013;2:e01096</Citation><ArticleIdList><ArticleId IdType="pubmed">24302568</ArticleId></ArticleIdList></Reference><Reference><Citation>Genomics. 2006 Jul;88(1):1-11</Citation><ArticleIdList><ArticleId IdType="pubmed">16631343</ArticleId></ArticleIdList></Reference><Reference><Citation>Structure. 2013 May 7;21(5):854-60</Citation><ArticleIdList><ArticleId IdType="pubmed">23562398</ArticleId></ArticleIdList></Reference><Reference><Citation>Proc Natl Acad Sci U S A. 2000 Aug 15;97(17):9519-24</Citation><ArticleIdList><ArticleId IdType="pubmed">10931948</ArticleId></ArticleIdList></Reference><Reference><Citation>Cell. 1986 Nov 7;47(3):371-80</Citation><ArticleIdList><ArticleId IdType="pubmed">3768958</ArticleId></ArticleIdList></Reference><Reference><Citation>Science. 2009 Feb 13;323(5916):943-6</Citation><ArticleIdList><ArticleId IdType="pubmed">19213920</ArticleId></ArticleIdList></Reference><Reference><Citation>Nature. 2012 Oct 25;490(7421):566-9</Citation><ArticleIdList><ArticleId IdType="pubmed">23000902</ArticleId></ArticleIdList></Reference><Reference><Citation>Oncology. 2013;84(6):362-70</Citation><ArticleIdList><ArticleId IdType="pubmed">23689165</ArticleId></ArticleIdList></Reference><Reference><Citation>Chembiochem. 2009 Sep 4;10(13):2223-9</Citation><ArticleIdList><ArticleId IdType="pubmed">19623597</ArticleId></ArticleIdList></Reference><Reference><Citation>J Chem Ecol. 2006 Jun;32(6):1181-96</Citation><ArticleIdList><ArticleId IdType="pubmed">16770712</ArticleId></ArticleIdList></Reference><Reference><Citation>Br J Pharmacol. 2011 Dec;164(7):1767-79</Citation><ArticleIdList><ArticleId IdType="pubmed">21175590</ArticleId></ArticleIdList></Reference><Reference><Citation>J Exp Zool. 1974 May;188(2):225-33</Citation><ArticleIdList><ArticleId IdType="pubmed">4133038</ArticleId></ArticleIdList></Reference><Reference><Citation>Exp Cell Res. 2009 Jan 15;315(2):190-205</Citation><ArticleIdList><ArticleId IdType="pubmed">19010322</ArticleId></ArticleIdList></Reference><Reference><Citation>Hum Mol Genet. 2006 Mar 15;15(6):953-64</Citation><ArticleIdList><ArticleId IdType="pubmed">16467350</ArticleId></ArticleIdList></Reference><Reference><Citation>Annu Rev Entomol. 2010;55:207-25</Citation><ArticleIdList><ArticleId IdType="pubmed">19725772</ArticleId></ArticleIdList></Reference><Reference><Citation>FEBS J. 2011 Sep;278(18):3226-45</Citation><ArticleIdList><ArticleId IdType="pubmed">21740521</ArticleId></ArticleIdList></Reference><Reference><Citation>IUBMB Life. 2012 Oct;64(10):795-800</Citation><ArticleIdList><ArticleId IdType="pubmed">23008114</ArticleId></ArticleIdList></Reference><Reference><Citation>Arch Insect Biochem Physiol. 2012 Jan;79(1):47-60</Citation><ArticleIdList><ArticleId IdType="pubmed">23589220</ArticleId></ArticleIdList></Reference><Reference><Citation>Physiol Rev. 2006 Oct;86(4):1179-236</Citation><ArticleIdList><ArticleId IdType="pubmed">17015488</ArticleId></ArticleIdList></Reference><Reference><Citation>Drug Metabol Drug Interact. 2011;26(3):105-11</Citation><ArticleIdList><ArticleId IdType="pubmed">21942345</ArticleId></ArticleIdList></Reference><Reference><Citation>Curr Pharm Biotechnol. 2011 Apr;12(4):647-55</Citation><ArticleIdList><ArticleId IdType="pubmed">21118089</ArticleId></ArticleIdList></Reference><Reference><Citation>Am J Physiol Cell Physiol. 2008 Feb;294(2):C579-90</Citation><ArticleIdList><ArticleId IdType="pubmed">18160489</ArticleId></ArticleIdList></Reference><Reference><Citation>J Membr Biol. 2009 Sep;231(1):1-10</Citation><ArticleIdList><ArticleId IdType="pubmed">19806386</ArticleId></ArticleIdList></Reference><Reference><Citation>Cancer Metastasis Rev. 2013 Jun;32(1-2):211-27</Citation><ArticleIdList><ArticleId IdType="pubmed">23093326</ArticleId></ArticleIdList></Reference><Reference><Citation>Res Microbiol. 2001 Apr-May;152(3-4):211-29</Citation><ArticleIdList><ArticleId IdType="pubmed">11421270</ArticleId></ArticleIdList></Reference><Reference><Citation>Methods Enzymol. 1998;292:213-24</Citation><ArticleIdList><ArticleId IdType="pubmed">9711556</ArticleId></ArticleIdList></Reference><Reference><Citation>Science. 1985 Aug 16;229(4714):649-51</Citation><ArticleIdList><ArticleId IdType="pubmed">17739376</ArticleId></ArticleIdList></Reference><Reference><Citation>Circ Res. 2013 Jul 19;113(3):279-87</Citation><ArticleIdList><ArticleId IdType="pubmed">23720443</ArticleId></ArticleIdList></Reference><Reference><Citation>PLoS One. 2013;8(12):e84461</Citation><ArticleIdList><ArticleId IdType="pubmed">24391959</ArticleId></ArticleIdList></Reference><Reference><Citation>PLoS One. 2013;8(5):e63895</Citation><ArticleIdList><ArticleId IdType="pubmed">23696857</ArticleId></ArticleIdList></Reference><Reference><Citation>Biochim Biophys Acta. 1976 Nov 11;455(1):152-62</Citation><ArticleIdList><ArticleId IdType="pubmed">990323</ArticleId></ArticleIdList></Reference><Reference><Citation>Trends Endocrinol Metab. 2013 Jul;24(7):342-50</Citation><ArticleIdList><ArticleId IdType="pubmed">23415156</ArticleId></ArticleIdList></Reference><Reference><Citation>Genomics. 1988 Apr;2(3):231-9</Citation><ArticleIdList><ArticleId IdType="pubmed">3294162</ArticleId></ArticleIdList></Reference><Reference><Citation>Med Vet Entomol. 2008 Mar;22(1):48-54</Citation><ArticleIdList><ArticleId IdType="pubmed">18380653</ArticleId></ArticleIdList></Reference><Reference><Citation>Annu Rev Genomics Hum Genet. 2005;6:123-42</Citation><ArticleIdList><ArticleId IdType="pubmed">16124856</ArticleId></ArticleIdList></Reference><Reference><Citation>BMC Genomics. 2013;14:6</Citation><ArticleIdList><ArticleId IdType="pubmed">23324493</ArticleId></ArticleIdList></Reference><Reference><Citation>Proc Natl Acad Sci U S A. 1987 May;84(9):3004-8</Citation><ArticleIdList><ArticleId IdType="pubmed">3472246</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Biol Rep. 2012 Jul;39(7):7281-91</Citation><ArticleIdList><ArticleId IdType="pubmed">22311044</ArticleId></ArticleIdList></Reference><Reference><Citation>New Phytol. 2013 Feb;197(3):886-98</Citation><ArticleIdList><ArticleId IdType="pubmed">23252416</ArticleId></ArticleIdList></Reference><Reference><Citation>Pflugers Arch. 2007 Feb;453(5):601-10</Citation><ArticleIdList><ArticleId IdType="pubmed">16622704</ArticleId></ArticleIdList></Reference><Reference><Citation>Genes Cells. 2011 Dec;16(12):1159-67</Citation><ArticleIdList><ArticleId IdType="pubmed">22077638</ArticleId></ArticleIdList></Reference><Reference><Citation>J Neurobiol. 1994 Jan;25(1):23-34</Citation><ArticleIdList><ArticleId IdType="pubmed">7906712</ArticleId></ArticleIdList></Reference><Reference><Citation>Essays Biochem. 2011 Sep 7;50(1):63-83</Citation><ArticleIdList><ArticleId IdType="pubmed">21967052</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Cell Biol. 2005 Nov;25(22):9859-73</Citation><ArticleIdList><ArticleId IdType="pubmed">16260602</ArticleId></ArticleIdList></Reference><Reference><Citation>Cancer Res. 2004 Feb 15;64(4):1403-10</Citation><ArticleIdList><ArticleId IdType="pubmed">14973057</ArticleId></ArticleIdList></Reference><Reference><Citation>J Mol Biol. 2003 Aug 1;331(1):155-65</Citation><ArticleIdList><ArticleId IdType="pubmed">12875842</ArticleId></ArticleIdList></Reference><Reference><Citation>J Biol Chem. 2013 Aug 2;288(31):22658-69</Citation><ArticleIdList><ArticleId IdType="pubmed">23792964</ArticleId></ArticleIdList></Reference><Reference><Citation>Nat Rev Cancer. 2002 Jan;2(1):48-58</Citation><ArticleIdList><ArticleId IdType="pubmed">11902585</ArticleId></ArticleIdList></Reference><Reference><Citation>BMC Genomics. 2009;10:170</Citation><ArticleIdList><ArticleId IdType="pubmed">19383151</ArticleId></ArticleIdList></Reference><Reference><Citation>Science. 2009 Mar 27;323(5922):1718-22</Citation><ArticleIdList><ArticleId IdType="pubmed">19325113</ArticleId></ArticleIdList></Reference><Reference><Citation>Biochemistry. 2007 Aug 21;46(33):9443-52</Citation><ArticleIdList><ArticleId IdType="pubmed">17661442</ArticleId></ArticleIdList></Reference><Reference><Citation>Pigment Cell Melanoma Res. 2009 Dec;22(6):740-9</Citation><ArticleIdList><ArticleId IdType="pubmed">19725928</ArticleId></ArticleIdList></Reference><Reference><Citation>Nature. 2008 Nov 6;456(7218):53-9</Citation><ArticleIdList><ArticleId IdType="pubmed">18987734</ArticleId></ArticleIdList></Reference><Reference><Citation>Essays Biochem. 2011 Sep 7;50(1):161-78</Citation><ArticleIdList><ArticleId IdType="pubmed">21967057</ArticleId></ArticleIdList></Reference><Reference><Citation>Bioinformatics. 2003 Mar 22;19(5):651-2</Citation><ArticleIdList><ArticleId IdType="pubmed">12651724</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Cells. 2003 Apr 30;15(2):150-8</Citation><ArticleIdList><ArticleId IdType="pubmed">12803476</ArticleId></ArticleIdList></Reference><Reference><Citation>Pflugers Arch. 2007 Feb;453(5):693-702</Citation><ArticleIdList><ArticleId IdType="pubmed">17021796</ArticleId></ArticleIdList></Reference><Reference><Citation>Biochim Biophys Acta. 2009 May;1794(5):725-37</Citation><ArticleIdList><ArticleId IdType="pubmed">19135557</ArticleId></ArticleIdList></Reference><Reference><Citation>Proc Natl Acad Sci U S A. 2012 Jun 19;109(25):E1591-8</Citation><ArticleIdList><ArticleId IdType="pubmed">22635270</ArticleId></ArticleIdList></Reference></ReferenceList></PubmedData></pubmed><affiliations><list><country><li>Allemagne</li></country></list><tree><country name="Allemagne"><noRegion><name sortKey="Strauss, Anja S" sort="Strauss, Anja S" uniqKey="Strauss A" first="Anja S" last="Strauss">Anja S. Strauss</name></noRegion><name sortKey="Boland, Wilhelm" sort="Boland, Wilhelm" uniqKey="Boland W" first="Wilhelm" last="Boland">Wilhelm Boland</name><name sortKey="Burse, Antje" sort="Burse, Antje" uniqKey="Burse A" first="Antje" last="Burse">Antje Burse</name><name sortKey="Gretscher, Rene R" sort="Gretscher, Rene R" uniqKey="Gretscher R" first="René R" last="Gretscher">René R. Gretscher</name><name sortKey="Groth, Marco" sort="Groth, Marco" uniqKey="Groth M" first="Marco" last="Groth">Marco Groth</name><name sortKey="Stock, Magdalena" sort="Stock, Magdalena" uniqKey="Stock M" first="Magdalena" last="Stock">Magdalena Stock</name><name sortKey="Wang, Ding" sort="Wang, Ding" uniqKey="Wang D" first="Ding" last="Wang">Ding Wang</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Bois/explor/PoplarV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001F96 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 001F96 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Bois
|area= PoplarV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= pubmed:24887102
|texte= Tissue-specific transcript profiling for ABC transporters in the sequestering larvae of the phytophagous leaf beetle Chrysomela populi.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:24887102" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a PoplarV1
| This area was generated with Dilib version V0.6.37. |  |